SCHOOL OF MEDICINE
C.P. Chang Laboratory
Cardiomyopathy and Vascular injury
We have generated a mouse model of cardiomyopathy and a mouse model that allows us to study the signaling events during the repair process following vascular injury such as balloon angioplasty. These models are directly relevant to a specific type of human congestive heart failure and the restenosis following angioplasty and stenting seen in clinical cardiology. We are investigating the pathogenesis of cardiomyopathy and the mechanisms of vascular restenosis following injury.