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Photo of Linda H Malkas, Ph.D.

Linda H Malkas, Ph.D.
Vera Bradley Professor Of Oncology; Professor; Adjunct Prof of PharmTox

Office:
Joseph E. Walther Hall, Room C312
980 W. Walnut St.
Indianapolis, IN 46202

Phone:  (317) 278-8260
E-mail:  lmalkas@iupui.edu


Research Interests:

1. Full Proteomic characterization of a multiprotein complex (the DNA synthesome), and its components, from human cells that is required for DNA replication.
2. Elucidation of molecular alterations that occur to the DNA synthesome as a function of malignancy, with and emphasis on breast cancer.
3. Identification of factors responsible for activation and regulation of the DNA synthesome.
4. Determining the mechanism of action of anticancer agents that affect cellular DNA synthesis.
5. Identification of novel biomarkers for the detection of cancer.
6. Identification of new molecular targets for the development of anticancer therapeutics.

Education and Training:

Postdoctoral Fellowship: Worchester Foundation for Experimental Biology
Ph.D.: City University of New York, New York, NY
Ph.M.: City University of New York, New York, NY

Recent Publications:

PubMed listings