The basic science research program within the Division of Hematology/Oncology spans a wide array of areas. Fundamental pathways from DNA replication and repair to integrated signaling pathways are currently under investigation as they relate to benign hematology and cancer. The role of stems cells, angiogenesis and tumor microenvironment are being studied in the context of cancer progression and metastasis. The analysis of biomarkers and drug development represents active areas of research with the goal of translating knowledge generated through basic science discovery to clinical application to impact human health. The Hematology/Oncology faculty is a prolific group publishing major findings in prestigious journals with extramural funding from the National Institutes of Health, Department of Defense, American Cancer Society and numerous agencies and foundations.