| Date |
Presenter |
Journal |
Title |
|
17-Jan
|
Nieves Velez de Mendizabal, Josiane Cardoso, Tyler Shugg (L)
|
n engl j med 369;24 |
A Randomized Trial of Genotype-Guided Dosing of Warfarin
|
|
24-Jan
|
Rich Bergstrom, Costantine Albany, Tonia Gardner (L)
|
doi: 10.1111/bcp.12322 |
Influence of covariate distribution on the predictive performance of pharmacokinetic models in paediatric research |
|
31-Jan
|
Sarah Quinney, Claire Li, Christina Chung (L) |
J Antimicrob Chemother 2014; 69: 180–189 doi:10.1093/jac/dkt304 |
Population pharmacokinetics of piperacillin and tazobactam in critically ill patients undergoing continuous renal replacement therapy: application to pharmacokinetic/pharmacodynamic analysis |
|
07-Feb
|
Michael Eadon, Kimberly Burgess, Heqiao Dai (L)
|
HEPATOLOGY 2013;58:1918-1929 |
Once-Daily Simeprevir (TMC435) With Pegylated Interferon and Ribavirin in Treatment-Na€ıve Genotype 1 Hepatitis C: The Randomized PILLAR Study |
|
|
14-Feb
|
Beth Pflug, Anna Schwartz, Nadia Falah (L)
|
Sci Transl Med 6, 221ra15 (2014) |
Antioxidants Accelerate Lung Cancer Progression in Mice |
|
21-Feb
|
David Thacker Bies, Nadia Falah, Noha Mourad (L)
|
Circ Cardiovasc Genet. 2013;6:313-316 |
Arrhythmia Risk in Long QT Syndrome Beyond the Disease-Causative Mutation |
|
21-Feb
|
Supplemental material
|
Circ Cardiovasc Genet. 2013;6:354-361 |
Identification of a KCNQ1 Polymorphism Acting as a Protective Modifier Against Arrhythmic Risk in Long-QT Syndrome |
|
28-Feb
|
Rolf Kreutz, Kruti Joshi, Heng Zhao (L)
|
N Engl J Med 2013;369:1206-14 |
Dabigatran versus Warfarin in Patients with Mechanical Heart Valves |
|
07-Mar
|
Tom Callaghan, Deshun Lu, Mike Ferguson (L)
|
J Clin Oncol 31:4562-4568 |
Evaluating Many Treatments and Biomarkers in Oncology: A New Design |
|
14-Mar
|
David Foster, Ayman Akil, Eric Benson (L)
|
Drug Metab Dispos 41:1514–1521 |
In Vivo Assessment of the Impact of Efflux Transporter on Oral Drug Absorption Using Portal Vein–Cannulated Rats |
|
21-Mar
|
No Journal Club - ASCPT
|
|
|
|
28-Mar
|
No Journal Club- 4th Year Course
|
|
|
|
4-Apr
|
Lang Li, Rebecca Pierson, Jinzhong Liu (L)
|
Cell 149, 780–794, May 11, 2012 |
Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks; |
|
11-Apr
|
Brian Decker, Elizabeth Sierra Potchanant, Costantine Albany (L)
|
British Journal of Cancer (2014), 1–8 | doi: 10.1038/bjc.2014.128 |
Aza-deoxycytidine induces apoptosis or differentiation via DNMT3B and targets embryonal carcinoma cells but not their differentiated derivatives
|
|
18-Apr
|
Zeruesenay Desta, Abhishek Gulati, Josiane Cardoso (L)
|
doi:10.1038/clpt.2013.241 |
Green Tea Ingestion Greatly Reduces Plasma Concentrations of Nadolol in Healthy Subjects |
|
25-Apr
|
David Flockhart, Smitha Marri, Deshun Lu (L)
|
doi:10.1038/clpt.2013.210 |
Identification and Characterization of a Defective CYP3A4 Genotype in a Kidney Transplant Patient With Severely Diminished Tacrolimus Clearance |
|
02-May
|
Jamie Renbarger, Ingrid Ferreira Metzger, Noha Moroud (L)
|
Journal of the American College of Cardiology Vol. 62, No. 23, 2013 |
Mipomersen, an Apolipoprotein B Synthesis Inhibitor, Reduces Atherogenic Lipoproteins in Patients With Severe Hypercholesterolemia at High Cardiovascular Risk |
|
09-May
|
Todd Skaar, Tyler Shugg, Kruti Joshi (L)
|
DOI: 10.1097/FTD.0000000000000080 |
CYP3A5*3 and POR*28 genetic variants influence the required dose of tacrolimus in heart transplant recipients |
|
16-May
|
David Haas, Christina Chung, Anna Schwartz (L)
|
Antimicrob. Agents Chemother. 2014, 58(5):2830. DOI:10.1128/AAC.01718-13. |
Determination of Vancomycin Pharmacokinetics in Neonates To Develop Practical Initial Dosing Recommendations |
|
23-May
|
Avi Patil, Mike Ferguson, Ayman Akil (L)
|
PLoS ONE 8(9): e74404. doi:10.1371, September 2013 | Volume 8 | Issue 9 | e74404 |
Multicompartmental Pharmacokinetic Model of Tenofovir Delivery by a Vaginal Gel |
|
30-May
|
No Journal Club
|
|
|
|
06-Jun
|
David Jones, Nadia Falah, Rebecca Pierson (L)
|
JAMA Pediatr. doi:10.1001/jamapediatrics.2013.4914 |
Acetaminophen Use During Pregnancy, Behavioral Problems, and Hyperkinetic Disorders |
|
13-Jun
|
Ken Levy, Jinzhong Liu, Kimberly Burgess (L)
|
N Engl J Med 2013;368:1685-94 DOI: 10.1056/NEJMoa1209026 |
Treatment of HCV Infection by Targeting MicroRNA |
|
|
20-Jun
|
Rob Bies, Heqaio Dai, Abhishek Gulati (L)
|
J Thromb Haemost 2014; 12: 902–9.DOI: 10.1111/jth.12564 |
No effect of isolated long-term supine immobilization or profound prolonged hypoxia on blood coagulation |
|
27-Jun
|
Brian Overholser, Tonia Gardner, Eric Benson (L)
|
Clinica l pharmac ology & Therapeut ics | VOLUME 95 NUMBER 4 | april 2014 doi:10.1038/clpt.2013.229 |
Clinically Actionable Genotypes Among 10,000 Patients With Preemptive Pharmacogenomic Testing |
|
18-July
|
Sara Quinney, Josiane Cardoso, Smitha Marri (L)
|
CLINICAL PHARMACOLOGY & THERAPEUTICS | VOLUME 96 NUMBER 1 | JULY 2014, doi:10.1038/clpt.2014.63 |
Sorafenib Dose Escalation Is Not Uniformly Associated With Blood Pressure Elevations in Normotensive Patients With Advanced Malignancies |
|
25-July
|
Tom Callaghan, Ayman Akil, Ingrid Ferreira Metzger (L)
|
NATURE COMMUNICATIONS 4 May 2013 | Accepted 27 Mar 2014 | Published 6 May 2014; DOI: 10.1038/ncomms4739 |
High-throughput and combinatorial gene expression on a chip for metabolism-induced toxicology screening |
|
1-Aug
|
Michael Eadon, Anna Schwartz, Christina Chung (L)
|
Clinical pharmacology & Therapeutics: doi:10.1038/clpt.2014.131 |
Pulmonary Penetration of Piperacillin and Tazobactam in Critically Ill Patients |
|
8-Aug
|
Rich Bergstrom, Noha Mourad, Heng Zhao (L)
|
TR-05530; doi:/10.1016/j.thromres.2014.05.019 |
The influence of body size on the pharmacodynamic and pharmacokinetic response to clopidogrel and prasugrel: A retrospective analysis of the FEATHER study |
|
15-Aug
|
Beth Pflug, Elizabeth Sierra Potchanant, Tyler Shugg (L)
|
The Journal of Clinical Pharmacology 54(8) 896–900© 2014, The American College of Clinical Pharmacology; DOI: 10.1002/jcph.332 |
Identification of VKORC1 Genotype Leading to Resistance to Tecarfarin |
|
22-Aug
|
Rob Bies, Rebecca Pierson, Kimberly Burgess (L)
|
Blood First Edition Paper, prepublished online May 14, 2014; DOI 10.1182/blood-2014-01-552166 |
Adherence to oral 6-mercaptopurine in African American and Asian children with acute lymphoblastic leukemia: a Children’s Oncology Group study |
|
29-Aug
|
David Flockhart, Jacob Zucker, Jinzhong Liu (L)
|
J Pharmacokinet Pharmacodyn; DOI 10.1007/s10928-012-9271-3 |
Modeling of Functional Assessment Questionnaire (FAQ) as continuous bounded data from the ADNI database |
|
5-Sept
|
Costantine Albany, Abhishek Gulati, Anna Schwartz (L)
|
Anesthesiology, V XXX • No XXX; doi;10.1097/ALN.0000000000000391 |
Cyclosporine-inhibitable Cerebral Drug Transport Does Not Influence Clinical Methadone Pharmacodynamics |
|
12- Sept
|
Zeruesenay Desta, Mustafa Hyder, Josiane Cardoso (L)
|
Clinical Pharmacology & Therapeutics; doi10.1038/clpt.2014.141 |
Glucuronidation Converts Clopidogrel to a Strong Time-Dependent Inhibitor of CYP2C8: A Phase II Metabolite as a Perpetrator of Drug–Drug Interactions |
|
19-Sept
|
Lang Li, Ingrid Ferreira Metzger, Ayman Akil (L)
|
BMJ Open 2013;3:e001844. doi:10.1136/bmjopen-2012-001844 |
A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4inhibitors, sitagliptin and linagliptin, in treatment of type 2 diabetes mellitus |
|
26-Sept
|
No Journal Club - CTSI Annual Meeting
|
|
|
|
3-Oct
|
David Foster, Tyler Shugg, Christina Chung (L)
|
Antimicrob. Agents Chemother. 2014, 58(7):3744. DOI: 10.1128/AAC.02089-13 |
Population Pharmacokinetic Analysis of Piperacillin in Burn Patients |
|
10-Oct
|
Jamie Renbarger, Deshun Lu, Rebecca Pierson (L)
|
Pharmacogenetics and Genomics 24:348–355; DOI: 10.1097/FPC.0000000000000061 |
Cancer patients’ acceptance, understanding, and willingness-to-pay for pharmacogenomic testing |
|
17-Oct
|
Todd Skaar, Noha Mourad, Jacob Zucker (L)
|
NATURE VOLUME 95 NUMBER 6 JUNE 2014; doi: 10.1038/clpt.2014.37 |
Integrating Cell-Based and Clinical Genome-Wide Studies to Identify Genetic Variants Contributing to Treatment Failure in Neuroblastoma Patients |
|
24-Oct
|
No Journal Club - Gladstein Lecture
|
|
|
|
31--Oct
|
Avi Patil, Ayman Akil, Mustafa Hyder (L)
|
J Clin Oncol 32:1317-1323. © 2014 by American Society of Clinical Oncology; DOI: 10.1200/JCO.2013.52.4298 |
Physicians’ Attitudes About Multiplex Tumor Genomic Testing |
|
7-Nov
|
Jim Tisdale, Kimberly Burgess, Deshun Lu (L)
|
The Journal of Clinical Pharmacology 54(11) 1272–1279 © 2014, The American College of Clinical Pharmacology; DOI: 10.1002/jcph.333 |
Potential Interactions Between HIV Drugs, Ritonavir and Efavirenz and Anticancer Drug, Nilotinib—A Study in Primary Cultures of Human Hepatocytes That Is Applicable to HIV Patients With Cancer |
|
14-Nov
|
David Jones, Elizabeth Sierra Potchanant, Ingrid Ferreira Metzger (L)
|
Clinical pharmacology & Therapeutics | VOLUME 96 NUMBER 3 | September 2014; DOI:10.1038/clpt.2014.83 |
Geneva Cocktail for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood Spots |
|
21-Nov
|
Ken Levy, Noha Mourad,Tyler Shugg (L)
|
© 2014 by the American College of Cardiology Foundation |
G-Protein Beta-3 Subunit Genotype Predicts Enhanced Benefit of Fixed-Dose Isosorbide Dinitrate and Hydralazine |
|
28-Nov
|
No Journal Club - Thanksgiving Holiday
|
|
|
|
5-Dec
|
Mike Ferguson, Rebecca Pierson, Anna Schwartz (L)
|
Early Human Development 90S1 (2014) S60–S65 |
Bovine lactoferrin supplementation for prevention of necrotizing enterocolitis in very-low-birth-weight neonates: a randomized clinical trial |
|
12-Dec
|
David Haas, Jacob Zucker, Abdullah Assiri (L)
|
Clin Trans Sci 2014; Volume 7: 396–401 |
CYP2C9 Allelic Variants and Frequencies in a Pediatric Sickle Cell Disease Cohort: Implications for NSAIDs Pharmacotherapy |
|
19-Dec
|
Brian Overholser, Mustafa Hyder, Kimberly Burgess (L)
|
PLoS ONE 9(2): e88164. doi:10.1371/journal.pone.0088164 |
Herg K+ Channel-Dependent Apoptosis and Cell Cycle Arrest in Human Glioblastoma Cells |
|
26-Dec
|
No Journal Club - Christmas Holiday
|
|
|
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|
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