| Date |
Presenter |
Journal |
Title |
| JAN 2 |
|
|
No Journal Club |
| JAN 9 |
Todd Skaar, PhD |
N Engl J Med. 2008 Dec 22. |
Cytochrome P-450 Polymorphisms and Response to Clopidogrel |
| JAN 16 |
|
|
No Journal Club |
| JAN 23 |
Kelley Krizek, Clin Pharm Grad Student |
Br J Pharmacol. 2007 Jun;151(3):384-95. |
Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro |
| JAN 30 |
Tom Callaghan, MD, PhD |
Blood. 2008 Apr 15;111(8):4106-12. |
CYP4F2 genetic variant alters required warfarin dose |
| FEB 6 |
Alette Wessels |
Diabetes. 2008 Feb;57(2):325-31. |
Glucagon-Like Peptide-1 Inhibits Blood-Brain Glucose Transfer in Humans |
| FEB 13 |
Brain Overholser |
Circulation. 2009 Jan 20;119(2):215-21. |
High Efficacy of 2-Blockers in Long-QT Syndrome Type 1: Contribution of Noncompliance and QT-Prolonging Drugs to the Occurrence of 2-Blocker Treatment "Failures" |
| FEB 20 |
Anne Nguyen |
J Clin Oncol. 2008 Feb 1;26(4):556-62. |
Adherence to initial adjuvant anastrozole therapy among women with early-stage breast cancer |
| FEB 27 |
|
|
No Journal Club |
| MAR 6 |
James Tisdale |
Arch Intern Med. 2008 Apr 28;168(8):826-31. |
Use of Alendronate and Risk of Incident Atrial Fibrillation in Women |
| MAR 13 |
|
|
|
| MAR 20 |
|
|
|
| MAR 27 |
|
|
|
| APR 3 |
|
|
|
| APR 10 |
|
|
|
| APR 17 |
YangWeon Kim |
Clin Pharmacol Ther. 2008 Jan;83(1):52-60. |
Cyclooxygenase Polymorphisms and Risk of Cardiovascular Events: The Atherosclerosis Risk in Communities (ARIC) Study |
| APR 24 |
Sherry Phillips |
Brain Res. 2008 Oct 9;1234:66-77. |
Inactivation of median preoptic nucleus causes c-Fos expression in hypocretin- and serotonin-containing neurons in anesthetized rat |
| MAY 1 |
Jason Robarge |
Nat Med. 2006 Nov;12(11):1269-77. |
GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence |
| MAY 8 |
David Thacker |
Clin Pharmacol Ther. 2008 Sep;84(3):347-61. |
Pharmacokinetics/Genotype Associations for Major Cytochrome P450 Enzymes in Native and First- and Third-generation Japanese Populations: Comparison With Korean, Chinese, and Caucasian Populations |
| MAY 15 |
Anuradha Ramamoorthy |
J Biol Chem. 2008 Nov 7;283(45):31079-86. |
MicroRNA-221/222 negatively regulates ERα and associates with tamoxifen resistance in breast cancer |
| MAY 22 |
Landry Kamdem |
Pharmacogenomics. 2008 Nov;9(11):1617-22. |
HLA-B locus in Japanese patients with anti-epileptics and allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis. |
| MAY 29 |
Jessie Lu |
Br J Clin Pharmacol. 2009 Apr;67(4):386-93. |
Morphine is an arteriolar vasodilator in man |
| JUN 5 |
Noam Epstein |
N Engl J Med. 2006 Oct 12;355(15):1525-38. |
Effectiveness of Atypical Antipsychotic Drugs in Patients with Alzheimer's Disease |
| JUN 12 |
David Haas |
N Engl J Med. 2009 Apr 16;360(16):1597-605.
N Engl J Med. 2009 Apr 16;360(16):1667-9. |
Cognitive Function at 3 Years of Age after Fetal Exposure to Antiepileptic Drugs.
Which Drug for the Pregnant Woman with Epilepsy? |
| JUN 19 |
Todd Skaar |
Clin Chem. 2009 55:8. |
CYP2D6 Genotyping for Functional-Gene Dosage Analysis by Allele Copy Number Detection |
| JUN 26 |
David Flockhart |
J Natl Cancer Inst. 1999 Dec 1;91(23):2001-8. |
Mercaptopurine Therapy Intolerance and Heterozygosity at the Thiopurine S-Methyltransferase Gene Locus |
| JUL 3 |
|
|
No Journal Club |
| JUL 10 |
Kelley Krizek |
Nat Med. 2009 Apr;15(4):417-24. |
Estrogen-dependent and C-C chemokine receptor-2–dependent pathways determine osteoclast behavior in osteoporosis |
| JUL 17 |
|
|
No Journal Club |
| JUL 24 |
John Callaghan |
Biochem Biophys Res Commun. 2008 Sep 19;374(2):341-4. |
Inflammation stimulates the expression of PCSK9 |
| JUL 31 |
Alette Wessels |
Diabetologia. 2009 Jun 30. |
Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: a cohort study |
| AUG 7 |
Brain Overholser |
Nat Med. 2009 Apr;15(4):380-3.
+ Supplemental Material |
Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans |
| AUG 14 |
Kelley Krizek |
|
Discuss experimental design for written proposal for qualifying exam. |
| AUG 21 |
|
|
No Journal Club |
| AUG 28 |
Ray Galinsky |
Hepatology. 2009 Aug;50(2):622-9. |
Constitutive Androstane Receptor Mediates the Induction of Drug Metabolism in Mouse Models of Type 1 Diabetes |
| SEP 4 |
Nikki Bell |
Hepatology. 2008 Aug;48(2):588-96. |
Glutathione S-Transferase M1 and T1 Null Genotypes Increase Susceptibility to Idiosyncratic Drug-Induced Liver Injury |
| SEP 11 |
Jason Robarge |
|
Mechanisms and genetic mediators of aromatase inhibitor-induced hypernociception |
| SEP 18 |
Beth Pflug |
ETS-PNAS
TMPRSS- COPA
|
ETS Family Transcription Factors Collaborate with Alternative Signaling Pathways to Induce Carcinoma from Adult Murine Prostate Cells |
| SEP 25 |
Doo-Yeoun Cho |
CPT. 2009 Aug 19. |
Association of Cyp2B6, Cyp3A5 and Cyp2C19 Genetic Polymorphisms with Sibtramine PK in Healthy Koreans. |
| OCT 2 |
Zeruesenay Desta |
Efavirenz vs Raltegravir (Editorial)
Efavirenz vs Raltegravir
|
Efavirenz vs Raltegravir |
| OCT 9 |
|
|
No Journal Club |
| OCT 16 |
David Flockhart |
Clin Pharmacol Ther. 2009 Oct;86(4):396-402. |
Contribution of Organic Cation Transporter 2 (OCT2) to Cisplatin-Induced Nephrotoxicity |
| OCT 23 |
Troy Quigg |
Pediatr Transplant. 2009 Jun;13(4):444-50. |
Pharmacokinetic monitoring of intravenous cyclosporine A in pediatric stem-cell transplant recipients. The trough level is not enough |
| OCT 30 |
David Haas |
Clin Pharmacokinet. 2009;48(10):677-83. |
Effect of Cytochrome P450 2D6 Genotype on Maternal Paroxetine Plasma Concentrations during Pregnancy |
| NOV 6 |
|
|
No Journal Club |
| NOV 13 |
Todd Skaar |
Nat Genet. 2009 Nov 8.
+ Supplemental Figures |
Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy |
| NOV 20 |
|
|
No Journal Club |
| NOV 27 |
Holiday |
|
No Journal Club |
| DEC 4 |
Tom Callaghan |
N Engl J Med. 2009 Sep 17;361(12):1139-51. |
Dabigatran versus Warfarin in Patients with Atrial Fibrillation |
| DEC 11 |
YangWeon Kim |
Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4402-7. |
Circulating microRNAs, potential biomarkers for drug-induced liver injury |
| DEC 18 |
|
|
No Journal Club |
| DEC 25 |
Happy Holidays |
|
No Journal Club |