| Date |
Presenter |
Journal |
Title |
| JAN 7 |
David Flockhart/Whitney Kramer |
Arch Intern Med. 2010 Jun 28. |
Rosiglitazone Revisited: An Updated Meta-analysis of Risk for Myocardial Infarction and Cardiovascular Mortality. |
| JAN 14 |
David Haas |
Obstet Gynecol. 2011 Jan;117(1):41-7. |
Effect of Injectable and Oral Contraceptives on Glucose and Insulin Levels. |
| JAN 21 |
Veronique Michaud |
PLoS One. 2010 Dec 13;5(12):e15064. |
VKORC1 Pharmacogenetics and Pharmacoproteomics in Patients on Warfarin Anticoagulant Therapy: Transthyretin Precursor as a Potential Biomarker |
| JAN 28 |
David Thacker |
|
Liver disease selectively modulates
cytochrome P450–mediated metabolism |
| FEB 4 |
Jessie Lu |
|
Competitive Displacement of Clozapine from Plasma Proteins in Normolipidemic and Hyperlipidemic Plasma Samples: Clinical Implications |
| FEB 11 |
Lateef Aregbe |
|
Iniparib plus Chemotherapy in Metastatic Triple-Negative Breast Cancer |
| FEB 18 |
Jon Duke |
|
Polypharmacoinformatics: Clinical Decision Support in Complex Drug Regimens |
| MAR 4 |
ASCPT |
|
|
| MAR 11 |
Sara Quinney |
|
Determination of a Quantitative Relationship between Hepatic CYP3A5*1/*3 and CYP3A4 Expression for Use in the Prediction of Metabolic Clearance in Virtual Populations |
| MAR 18 |
Spring Break |
|
|
| MAR 25 |
Eileen Han |
|
Drug-Drug Interactions Among Elderly Patients Hospitalized for Drug Toxicity |
| APR 8 |
Rich Bergstrom |
|
Mechanism-Based Inactivation of CYP2C8 by Gemfibrozil Occurs Rapidly in Humans |
| APR 15 |
Rolf Kreutz |
|
Paraoxonase-1 is a major determinant of clopidogrel efficacy |
| APR 22 |
Holiday |
|
|
| APR 29 |
Claire Xu |
|
Rifampin's Acute Inhibitory and Chronic Inductive Drug Interactions: Experimental and Model-Based Approaches to Drug–Drug Interaction Trial Design |
| MAY 13 |
Tom Callaghan |
|
Disease–Drug–Drug Interaction Involving Tocilizumab and Simvastatin in Patients With Rheumatoid Arthritis |
| MAY 20 |
Todd Skaar |
|
MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins |
| MAY 27 |
Holiday |
|
|
| JUN 3 |
Jason Robarge |
|
An ADIOL-ERb-CtBP Transrepression Pathway Negatively Regulates Microglia-Mediated Inflammation |
| JUN 10 |
David Haas |
|
Hypoglycemia in Glyburide-Treated Gestational Diabetes |
| JUN 17 |
Veronique Michaud |
|
Cellular localization and functional significance of CYP3A4 in the human epileptic brain |
| JUL 1 |
Rob Bies |
|
Tumor growth modeling from clinical trials reveals synergistic anticancer effect of the capecitabine and docetaxel combination in metastatic breast cancer |
| JUL 8 |
Desta |
|
Organic anion transporting polypeptide 1a/1b–knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs |
| JUL 22 |
Whitney Kramer |
|
Stopping Randomized Trials Early for Benefit and Estimation of Treatment Effects and Practical Problems in Interim Analyses, with Particular Regard to Estimation |
| JUL 29 |
Jessie Lu |
|
Aromatase Activity and Bone Loss in Men |
| AUG 5 |
James Tisdale |
J Am Coll Cardiol. 2011 Jun 28;58(1):40-4. |
Reconstituted High-Density Lipoprotein Shortens Cardiac Repolarization |
| AUG 12 |
Sara Quinney |
BMC Syst Biol. 2011 May 6;5(1):66. |
A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes |
| AUG 19 |
No Seminar |
|
|
| AUG 26 |
Lang Li |
|
Computer Search for Drug Discovery |
| SEP 2 |
Tom Callaghan |
|
Reboxetine & MDMA |
| SEP 9 |
Claire Li |
Atherosclerosis. 2011 Aug;217(2):458-64. |
Genetic variability within the cholesterol lowering pathway and the effectiveness of statins in reducing the risk of MI |
| SEP 16 |
Rolf Kreutz |
N Engl J Med. 2011 Sep 15;365(11):981-92. |
Apixaban versus Warfarin in Patients with Atrial Fibrillation |
| SEP 30 |
No Seminar |
|
|
| OCT 7 |
Lang Li, Eric Sherer, Claire Li, and Sara Quinney |
N Engl J Med. 2011 Aug 3. |
Lebrikizumab Treatment in Adults with Asthma |
| OCT 14 |
Rob Bies, Tonia Thompson, Heng Zhao, Brian Overholser |
J Pharmacokinet Pharmacodyn. 2011 Oct;38(5):595-612. |
Modelling of the outcome of non-inferiority trials by integration of historical data |
| OCT 21 |
Jamie Renbarger, Jasper Stevens, Jason Robarge, Jim Tisdale |
Br J Clin Pharmacol. 2011 Sep;72(3):454-64. |
Paediatric drug development: are population models predictive of pharmacokinetics across paediatric populations? |
| OCT 28 |
David Jones, David Thacker, Rebecca Lynch, Rolf Kreutz |
Drug Metab Dispos. 2011 Apr;39(4):703-10. |
In Vitro Evaluation of Potential Drug-Drug Interactions with Ticagrelor: Cytochrome P450 Reaction Phenotyping, Inhibition, Induction, and Differential Kinetics |
| NOV 4 |
David Flockhart, Ingrid Metzger, Whitney Kramer, David Haas |
J Clin Psychiatry. 2010 Nov;71(11):1482-7. |
Cytochrome P450 2D6 phenotype predicts antidepressant efficacy of venlafaxine: a secondary analysis of 4 studies in major depressive disorder. |
| NOV 11 |
Todd Skaar, Eric Benson, Claire Xu, Rich Bergstrom |
Molecular Systems Biology 7:513; July 2011, Pages 1-13 |
A pharmacogenomic method for individualized prediction of drug sensitivity |
| NOV 18 |
Eileen Han, Tom Callaghan, Heqaio Dai, and Zereusenay Desta |
Clinical Pharmacology & Therapeutics 90(4): 575-581. |
Identification of the Rate-Determining Process in the Hepatic Clearance of Atorvastatin in a Clinical Cassette Microdosing Study |
| NOV 25 |
Holiday |
|
|
| DEC 2 |
Beth Pflug, Veronique Michaud, Santosh Philips, Anne Nguyen |
N Engl J Med. 2011 May 26;364(21):1995-2005. |
Abiraterone and Increased Survival in Metastatic Prostate Cancer |
| DEC 9 |
Lang Li, Deshun Lu, and Christina Chung (L) |
Journal of the American College of Cardiology 2011, Vol. 58, No. 16 |
Benefit of Early Statin Therapy in Patients With Acute Myocardial Infarction Who Have Extremely Low Low-Density Lipoprotein Cholesterol |
| DEC 16 |
Canceled |
|
|
| DEC 23 |
Holiday |
|
|
| DEC 30 |
Holiday |
|
|