Friday Journal Club (2009)
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Journal Club meets on Fridays from 8:00am-10:30am in conference room W7120 (Wishard Myers Bldg., 7th Floor). Please email a copy of your article in PDF format to April Baker. 2010 Schedule | 2009 Schedule | 2008 Schedule | 2007 Schedule |
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| Date | Presenter | Journal | Title |
| JAN 2 | No Journal Club | ||
| JAN 9 | Todd Skaar, PhD | N Engl J Med. 2008 Dec 22. | Cytochrome P-450 Polymorphisms and Response to Clopidogrel |
| JAN 16 | No Journal Club | ||
| JAN 23 | Kelley Krizek, Clin Pharm Grad Student | Br J Pharmacol. 2007 Jun;151(3):384-95. | Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro |
| JAN 30 | Tom Callaghan, MD, PhD | Blood. 2008 Apr 15;111(8):4106-12. | CYP4F2 genetic variant alters required warfarin dose |
| FEB 6 | Alette Wessels | Diabetes. 2008 Feb;57(2):325-31. | Glucagon-Like Peptide-1 Inhibits Blood-Brain Glucose Transfer in Humans |
| FEB 13 | Brain Overholser | Circulation. 2009 Jan 20;119(2):215-21. | High Efficacy of 2-Blockers in Long-QT Syndrome Type 1: Contribution of Noncompliance and QT-Prolonging Drugs to the Occurrence of 2-Blocker Treatment "Failures" |
| FEB 20 | Anne Nguyen | J Clin Oncol. 2008 Feb 1;26(4):556-62. | Adherence to initial adjuvant anastrozole therapy among women with early-stage breast cancer |
| FEB 27 | No Journal Club | ||
| MAR 6 | James Tisdale | Arch Intern Med. 2008 Apr 28;168(8):826-31. | Use of Alendronate and Risk of Incident Atrial Fibrillation in Women |
| MAR 13 | |||
| MAR 20 | |||
| MAR 27 | |||
| APR 3 | |||
| APR 10 | |||
| APR 17 | YangWeon Kim | Clin Pharmacol Ther. 2008 Jan;83(1):52-60. | Cyclooxygenase Polymorphisms and Risk of Cardiovascular Events: The Atherosclerosis Risk in Communities (ARIC) Study |
| APR 24 | Sherry Phillips | Brain Res. 2008 Oct 9;1234:66-77. | Inactivation of median preoptic nucleus causes c-Fos expression in hypocretin- and serotonin-containing neurons in anesthetized rat |
| MAY 1 | Jason Robarge | Nat Med. 2006 Nov;12(11):1269-77. | GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence |
| MAY 8 | David Thacker | Clin Pharmacol Ther. 2008 Sep;84(3):347-61. | Pharmacokinetics/Genotype Associations for Major Cytochrome P450 Enzymes in Native and First- and Third-generation Japanese Populations: Comparison With Korean, Chinese, and Caucasian Populations |
| MAY 15 | Anuradha Ramamoorthy | J Biol Chem. 2008 Nov 7;283(45):31079-86. | MicroRNA-221/222 negatively regulates ERα and associates with tamoxifen resistance in breast cancer |
| MAY 22 | Landry Kamdem | Pharmacogenomics. 2008 Nov;9(11):1617-22. | HLA-B locus in Japanese patients with anti-epileptics and allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis. |
| MAY 29 | Jessie Lu | Br J Clin Pharmacol. 2009 Apr;67(4):386-93. | Morphine is an arteriolar vasodilator in man |
| JUN 5 | Noam Epstein | N Engl J Med. 2006 Oct 12;355(15):1525-38. | Effectiveness of Atypical Antipsychotic Drugs in Patients with Alzheimer’s Disease |
| JUN 12 | David Haas | N Engl J Med. 2009 Apr 16;360(16):1597-605. N Engl J Med. 2009 Apr 16;360(16):1667-9. |
Cognitive Function at 3 Years of Age after Fetal Exposure to Antiepileptic Drugs. Which Drug for the Pregnant Woman with Epilepsy? |
| JUN 19 | Todd Skaar | Clin Chem. 2009 55:8. | CYP2D6 Genotyping for Functional-Gene Dosage Analysis by Allele Copy Number Detection |
| JUN 26 | David Flockhart | J Natl Cancer Inst. 1999 Dec 1;91(23):2001-8. | Mercaptopurine Therapy Intolerance and Heterozygosity at the Thiopurine S-Methyltransferase Gene Locus |
| JUL 3 | No Journal Club | ||
| JUL 10 | Kelley Krizek | Nat Med. 2009 Apr;15(4):417-24. | Estrogen-dependent and C-C chemokine receptor-2–dependent pathways determine osteoclast behavior in osteoporosis |
| JUL 17 | No Journal Club | ||
| JUL 24 | John Callaghan | Biochem Biophys Res Commun. 2008 Sep 19;374(2):341-4. | Inflammation stimulates the expression of PCSK9 |
| JUL 31 | Alette Wessels | Diabetologia. 2009 Jun 30. | Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: a cohort study |
| AUG 7 | Brain Overholser | Nat Med. 2009 Apr;15(4):380-3. + Supplemental Material |
Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans |
| AUG 14 | Kelley Krizek | Preliminary Proposal | Discuss experimental design for written proposal for qualifying exam. |
| AUG 21 | No Journal Club | ||
| AUG 28 | Ray Galinsky | Hepatology. 2009 Aug;50(2):622-9. | Constitutive Androstane Receptor Mediates the Induction of Drug Metabolism in Mouse Models of Type 1 Diabetes |
| SEP 4 | Nikki Bell | Hepatology. 2008 Aug;48(2):588-96. | Glutathione S-Transferase M1 and T1 Null Genotypes Increase Susceptibility to Idiosyncratic Drug-Induced Liver Injury |
| SEP 11 | Jason Robarge | Research Proposal | Mechanisms and genetic mediators of aromatase inhibitor-induced hypernociception |
| SEP 18 | Beth Pflug | ETS Family Transcription Factors Collaborate with Alternative Signaling Pathways to Induce Carcinoma from Adult Murine Prostate Cells | |
| SEP 25 | Doo-Yeoun Cho | CPT. 2009 Aug 19. | Association of Cyp2B6, Cyp3A5 and Cyp2C19 Genetic Polymorphisms with Sibtramine PK in Healthy Koreans. |
| OCT 2 | Zeruesenay Desta | Efavirenz vs Raltegravir | |
| OCT 9 | No Journal Club | ||
| OCT 16 | David Flockhart | Clin Pharmacol Ther. 2009 Oct;86(4):396-402. | Contribution of Organic Cation Transporter 2 (OCT2) to Cisplatin-Induced Nephrotoxicity |
| OCT 23 | Troy Quigg | Pediatr Transplant. 2009 Jun;13(4):444-50. | Pharmacokinetic monitoring of intravenous cyclosporine A in pediatric stem-cell transplant recipients. The trough level is not enough |
| OCT 30 | David Haas | Clin Pharmacokinet. 2009;48(10):677-83. | Effect of Cytochrome P450 2D6 Genotype on Maternal Paroxetine Plasma Concentrations during Pregnancy |
| NOV 6 | No Journal Club | ||
| NOV 13 | Todd Skaar | Nat Genet. 2009 Nov 8. + Supplemental Figures |
Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy |
| NOV 20 | Jamie Renbarger | ||
| NOV 27 | Holiday | No Journal Club | |
| DEC 4 | Tom Callaghan | ||
| DEC 11 | Troy Quigg | ||
| DEC 18 | Lang Li | ||
| DEC 25 | Happy Holidays | No Journal Club | |



