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References for Cytochrome P450 Drug Interaction Table Part 2 of 7: 2B6 Isoform These pages contain all the literature citations referenced in the Cytochrome P450 Drug Interaction Tables (both the extensive research-oriented table and the concise clinical table). Most of these citations are hyperlinks, which bring up the abstract in the NLM's PubMed® database. Click on the PubMed link after the drug name to perform a live MedLINE search of articles possibly related to that drug and Cytochrome P450. Entries are organized by mode of activity (substrate, inhibitor, inducer) within specific isoform. You can quickly branch to a section by clicking on the appropriate link here:
Hint: a quick way to find a specific reference on this page is to use your web browser's Search feature: press Ctrl-F and type all or part of the name or word for which you are searching.
Validation of bupropion hydroxylation as a selective marker of human cytochrome P450 2B6 catalytic activity. cyclophosphamide: Info PubMed
Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes. ifosphamide: Info PubMed
Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes.
Role of CYP2B6 and CYP3A4 in the in vitro N-dechloroethylation of (R)- and (S)-ifosfamide in human liver microsomes. 
Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: Implications for cyclophosphamide metabolism. ticlopidine: Info PubMed
phenobarbital: Info PubMed
Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: Response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines.
Phenytoin-induced alteration in the N-dechloroethylation of ifosfamide stereoisomers.
Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: Response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines.
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