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References for Cytochrome P450 Drug Interaction Table Part 6 of 7: 2E1 Isoform These pages contain all the literature citations referenced in the Cytochrome P450 Drug Interaction Tables (both the extensive research-oriented table and the concise clinical table). Most of these citations are hyperlinks, which bring up the abstract in the NLM's PubMed® database. Click on the PubMed link after the drug name to perform a live MedLINE search of articles possibly related to that drug and Cytochrome P450. Entries are organized by mode of activity (substrate, inhibitor, inducer) within specific isoform. You can quickly branch to a section by clicking on the appropriate link here:
Hint: a quick way to find a specific reference on this page is to use your web browser's Search feature: press Ctrl-F and type all or part of the name or word for which you are searching.
Acetaminophen activation by human liver cytochrome P450 2E1 and
1A2.
Requirements for cytochrome b5 in the
oxidation of 7-ethoxycoumarin, chlorzoxazone, aniline, and N-nitrosodimethylamine
by recombinant cytochrome P450 2E1 and by human liver microsomes.
Benzene poisoning, a risk factor for hematological malignancy, is associated
with the NQO1 609C-->T mutation and rapid fractional excretion of
chlorzoxazone.
Hydroxylation of chlorzoxazone as a specific probe
for human liver cytochrome P4502E1.
Stereoselective metabolism of enflurane by human liver cytochrome P450
2E1.
Clinical enflurane metabolism by cytochrome P450 2E1.
Cytochrome P450 2E1 is the principal catalyst of human oxidative halothane
metabolism in vitro.
Interindividual variability in P450-dependent generation of neoantigens
in halothane hepatitis.
Investigation of the mechanistic basis of N,N-dimethylformamide toxicity.
Metabolism of N,N-dimethylformamide and its deuterated isotopomers by cytochrome
P450 2E1.
Dose-dependent inhibition of theophylline metabolism by disulfiram in
recovering alcoholics.
diethyl-dithiocarbamate: PubMed
Role of human cytochrome P450 2E1 in the oxidation
of many low molecular weight cancer suspects.
Single dose disulfiram inhibition of chlorzoxazone
metabolism: A clinical probe for P450 2E1.
Inhibition and induction of cytochrome P4502E1-catalyzed oxidation by
isoniazid in humans. |