SUBSTRATES
1A2	2B6	2C8	2C19	2C9	2D6	2E1	3A4,5,7
clozapine cyclobenzaprine imipramine mexiletine naproxen riluzole tacrine theophylline	bupropion cyclophosphamide efavirenz ifosfamide methadone		Proton Pump Inhibitors: omeprazole lansoprazole pantoprazole rabeprazole Anti-epileptics: diazepam phenytoin phenobarbitone amitriptyline clomipramine clopidogrel cyclophosphamide progesterone	NSAIDs: diclofenac ibuprofen piroxicam Oral Hypoglycemic Agents: tolbutamide glipizide Angiotensin II Blockers: NOT candesartan irbesartan losartan NOT valsartan celecoxib fluvastatin naproxen phenytoin sulfamethoxazole tamoxifen tolbutamide torsemide warfarin	Beta Blockers: S-metoprolol propafenone timolol Antidepressants: amitriptyline clomipramine desipramine imipramine paroxetine Antipsychotics: haloperidol risperidone thioridazine aripiprazole codeine dextromethorphan duloxetine flecainide mexiletine ondansetron tamoxifen tramadol venlafaxine	acetaminophen chlorzoxazone ethanol	Macrolide antibiotics: clarithromycin erythromycin NOT azithromycin telithromycin Anti-arrhythmics: quinidine Benzodiazepines: alprazolam diazepam midazolam triazolam Immune Modulators: cyclosporine tacrolimus (FK506) HIV Protease Inhibitors: indinavir ritonavir saquinavir Prokinetic: cisapride Antihistamines: astemizole chlorpheniramine Calcium Channel Blockers: amlodipine diltiazem felodipine nifedipine nisoldipine nitrendipine verapamil HMG CoA Reductase Inhibitors: atorvastatin cerivastatin lovastatin NOT pravastatin simvastatin aripiprazole buspirone gleevec haloperidol (in part) methadone pimozide quinine NOT rosuvastatin sildenafil tamoxifen trazodone vincristine
INHIBITORS
1A2	2B6	2C8	2C19	2C9	2D6	2E1	3A4,5,7
cimetidine fluoroquinolones fluvoxamine ticlopidine	thiotepa ticlopidine	gemfibrozil montelukast	fluoxetine fluvoxamine ketoconazole lansoprazole omeprazole ticlopidine	amiodarone fluconazole isoniazid	amiodarone buproprion chlorpheniramine cimetidine clomipramine duloxetine fluoxetine haloperidol methadone mibefradil paroxetine quinidine ritonavir	disulfiram	HIV Protease Inhibitors: indinavir nelfinavir ritonavir amiodarone NOT azithromycin cimetidine clarithromycin diltiazem erythromycin fluvoxamine grapefruit juice itraconazole ketoconazole mibefradil nefazodone troleandomycin verapamil
INDUCERS
1A2	2B6	2C8	2C19	2C9	2D6	2E1	3A4,5,7
tobacco	phenobarbital phenytoin rifampin		N/A	rifampin secobarbital	N/A	ethanol isoniazid	carbamazepine phenobarbital phenytoin rifabutin rifampin St. John's wort troglitazone