SCHOOL OF MEDICINE

Department of Medicine

Nephrology

Newly Published

1.            Barwinska, D.;  El-Achkar, T. M.;  Melo Ferreira, R.;  Syed, F.;  Cheng, Y. H.;  Winfree, S.;  Ferkowicz, M. J.;  Hato, T.;  Collins, K. S.;  Dunn, K. W.;  Kelly, K. J.;  Sutton, T. A.;  Rovin, B. H.;  Parikh, S. V.;  Phillips, C. L.;  Dagher, P. C.; Eadon, M. T., Molecular characterization of the human kidney interstitium in health and disease. Sci Adv 2021, 7 (7).

2.            Barwinska, D.;  Ferkowicz, M. J.;  Cheng, Y. H.;  Winfree, S.;  Dunn, K. W.;  Kelly, K. J.;  Sutton, T. A.;  Rovin, B. H.;  Parikh, S. V.;  Phillips, C. L.;  Dagher, P. C.;  El-Achkar, T. M.; Eadon, M. T., Application of Laser Microdissection to Uncover Regional Transcriptomics in Human Kidney Tissue. J Vis Exp 2020,  (160).

3.            Canela, V. H.;  Bledsoe, S. B.;  Lingeman, J. E.;  Gerber, G.;  Worcester, E. M.;  El-Achkar, T. M.; Williams, J. C., Jr., Demineralization and sectioning of human kidney stones: A molecular investigation revealing the spatial heterogeneity of the stone matrix. Physiol Rep 2021, 9 (1), e14658.

4.            de Boer, I. H.;  Alpers, C. E.;  Azeloglu, E. U.;  Balis, U. G. J.;  Barasch, J. M.;  Barisoni, L.;  Blank, K. N.;  Bomback, A. S.;  Brown, K.;  Dagher, P. C.;  Dighe, A. L.;  Eadon, M. T.;  El-Achkar, T. M.;  Gaut, J. P.;  Hacohen, N.;  He, Y.;  Hodgin, J. B.;  Jain, S.;  Kellum, J. A.;  Kiryluk, K.;  Knight, R.;  Laszik, Z. G.;  Lienczewski, C.;  Mariani, L. H.;  McClelland, R. L.;  Menez, S.;  Moledina, D. G.;  Mooney, S. D.;  O'Toole, J. F.;  Palevsky, P. M.;  Parikh, C. R.;  Poggio, E. D.;  Rosas, S. E.;  Rosengart, M. R.;  Sarwal, M. M.;  Schaub, J. A.;  Sedor, J. R.;  Sharma, K.;  Steck, B.;  Toto, R. D.;  Troyanskaya, O. G.;  Tuttle, K. R.;  Vazquez, M. A.;  Waikar, S. S.;  Williams, K.;  Wilson, F. P.;  Zhang, K.;  Iyengar, R.;  Kretzler, M.; Himmelfarb, J., Rationale and design of the Kidney Precision Medicine Project. Kidney Int 2021, 99 (3), 498-510.

5.            Eadon, M. T.;  Cheng, Y. H.;  Hato, T.;  Benson, E. A.;  Ipe, J.;  Collins, K. S.;  De Luca, T.;  El-Achkar, T. M.;  Bacallao, R. L.;  Skaar, T. C.; Dagher, P. C., In Vivo siRNA Delivery and Rebound of Renal LRP2 in Mice. J Drug Deliv 2017, 2017, 4070793.

6.            Eadon, M. T.;  Lampe, S.;  Baig, M. M.;  Collins, K. S.;  Melo Ferreira, R.;  Mang, H.;  Cheng, Y. H.;  Barwinska, D.;  El-Achkar, T. M.;  Schwantes-An, T. H.;  Winfree, S.;  Temm, C. J.;  Ferkowicz, M. J.;  Dunn, K. W.;  Kelly, K. J.;  Sutton, T. A.;  Moe, S. M.;  Moorthi, R. N.;  Phillips, C. L.; Dagher, P. C., Clinical, histopathologic and molecular features of idiopathic and diabetic nodular mesangial sclerosis in humans. Nephrol Dial Transplant 2021.

7.            El-Achkar, T. M.;  Eadon, M. T.;  Menon, R.;  Lake, B. B.;  Sigdel, T. K.;  Alexandrov, T.;  Parikh, S.;  Zhang, G.;  Dobi, D.;  Dunn, K. W.;  Otto, E. A.;  Anderton, C. R.;  Carson, J. M.;  Luo, J.;  Park, C.;  Hamidi, H.;  Zhou, J.;  Hoover, P.;  Schroeder, A.;  Joanes, M.;  Azeloglu, E. U.;  Sealfon, R.;  Winfree, S.;  Steck, B.;  He, Y.;  D'Agati, V.;  Iyengar, R.;  Troyanskaya, O. G.;  Barisoni, L.;  Gaut, J.;  Zhang, K.;  Laszik, Z.;  Rovin, B. H.;  Dagher, P. C.;  Sharma, K.;  Sarwal, M. M.;  Hodgin, J. B.;  Alpers, C. E.;  Kretzler, M.; Jain, S., A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project. Physiol Genomics 2021, 53 (1), 1-11.

8.            Ferkowicz, M. J.;  Winfree, S.;  Sabo, A. R.;  Kamocka, M. M.;  Khochare, S.;  Barwinska, D.;  Eadon, M. T.;  Cheng, Y. H.;  Phillips, C. L.;  Sutton, T. A.;  Kelly, K. J.;  Dagher, P. C.;  El-Achkar, T. M.; Dunn, K. W., Large-scale, three-dimensional tissue cytometry of the human kidney: a complete and accessible pipeline. Lab Invest 2021.

9.            Janosevic, D.;  Myslinski, J.;  McCarthy, T. W.;  Zollman, A.;  Syed, F.;  Xuei, X.;  Gao, H.;  Liu, Y. L.;  Collins, K. S.;  Cheng, Y. H.;  Winfree, S.;  El-Achkar, T. M.;  Maier, B.;  Melo Ferreira, R.;  Eadon, M. T.;  Hato, T.; Dagher, P. C., The orchestrated cellular and molecular responses of the kidney to endotoxin define a precise sepsis timeline. Elife 2021, 10.

10.          Micanovic, R.;  LaFavers, K.;  Garimella, P. S.;  Wu, X. R.; El-Achkar, T. M., Uromodulin (Tamm-Horsfall protein): guardian of urinary and systemic homeostasis. Nephrol Dial Transplant 2020, 35 (1), 33-43.

11.          Winfree, S.;  Weiler, C.;  Bledsoe, S. B.;  Gardner, T.;  Sommer, A. J.;  Evan, A. P.;  Lingeman, J. E.;  Krambeck, A. E.;  Worcester, E. M.;  El-Achkar, T. M.; Williams, J. C., Jr., Multimodal imaging reveals a unique autofluorescence signature of Randall's plaque. Urolithiasis 2021, 49 (2), 123-135.

12.          Woloshuk, A.;  Khochare, S.;  Almulhim, A. F.;  McNutt, A. T.;  Dean, D.;  Barwinska, D.;  Ferkowicz, M. J.;  Eadon, M. T.;  Kelly, K. J.;  Dunn, K. W.;  Hasan, M. A.;  El-Achkar, T. M.; Winfree, S., In Situ Classification of Cell Types in Human Kidney Tissue Using 3D Nuclear Staining. Cytometry A 2020.

13.          Adhyapok, P.;  Fu, X.;  Sluka, J. P.;  Clendenon, S. G.;  Sluka, V. D.;  Wang, Z.;  Dunn, K.;  Klaunig, J. E.; Glazier, J. A., A computational model of liver tissue damage and repair. PLoS One 2020, 15 (12), e0243451.

14.          Dunn, K. W.;  Martinez, M. M.;  Wang, Z.;  Mang, H. E.;  Clendenon, S. G.;  Sluka, J. P.;  Glazier, J. A.; Klaunig, J. E., Mitochondrial depolarization and repolarization in the early stages of acetaminophen hepatotoxicity in mice. Toxicology 2020, 439, 152464.

15.          Dunn, K. W.;  Molitoris, B. A.; Dagher, P. C., Indiana Center for Advanced Renal Microscopic Analysis. Am J Physiol Renal Physiol 2021.

16.          Ho, D. J.;  Mas Montserrat, D.;  Fu, C.;  Salama, P.;  Dunn, K. W.; Delp, E. J., Sphere estimation network: three-dimensional nuclei detection of fluorescence microscopy images. J Med Imaging (Bellingham) 2020, 7 (4), 044003.

17.          Reissaus, C. A.;  Day, K. H.;  Mirmira, R. G.;  Dunn, K. W.;  Pavalko, F. M.; Day, R. N., PIE-FLIM Measurements of Two Different FRET-Based Biosensor Activities in the Same Living Cells. Biophys J 2020, 118 (8), 1820-1829.

18.          Liu, X. F.;  Wei, J.;  Zhou, Q.;  Molitoris, B. A.;  Sandoval, R.;  Kobayashi, H.;  Okada, R.;  Nagaya, T.;  Karim, B.;  Butcher, D.; Pastan, I., Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to albumin loss in urine. Proc Natl Acad Sci U S A 2020, 117 (11), 6086-6091.

19.          Yadav, S. P. S.;  Sandoval, R. M.;  Zhao, J.;  Huang, Y.;  Wang, E.;  Kumar, S.;  Campos-Bilderback, S. B.;  Rhodes, G.;  Mechref, Y.;  Molitoris, B. A.; Wagner, M. C., Mechanism of how carbamylation reduces albumin binding to FcRn contributing to increased vascular clearance. Am J Physiol Renal Physiol 2021, 320 (1), F114-f129.

20.          Madhivanan, K.;  Ramadesikan, S.;  Hsieh, W. C.;  Aguilar, M. C.;  Hanna, C. B.;  Bacallao, R. L.; Aguilar, R. C., Lowe syndrome patient cells display mTOR- and RhoGTPase-dependent phenotypes alleviated by rapamycin and statins. Hum Mol Genet 2020, 29 (10), 1700-1715.