SCHOOL OF MEDICINE

Department of Medicine

Nephrology

Three-Dimensional Tissue Imaging Core

(LaFavers et al., 2019; Micanovic et al., 2019; Patidar et al., 2019; Winfree et al., 2018)

Micanovic, R., LaFavers, K., Garimella, P.S., Wu, X.R., El-Achkar, T.M., 2020. Uromodulin (Tamm-Horsfall protein): guardian of urinary and systemic homeostasis. Nephrol Dial Transplant 35, 33-43.
LaFavers, K.A., Macedo, E., Garimella, P.S., Lima, C., Khan, S., Myslinski, J., McClintick, J., Witzmann, F.A., Winfree, S., Phillips, C.L., Hato, T., Dagher, P.C., Wu, X.R., El-Achkar, T.M., Micanovic, R., 2019. Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel. Science translational medicine 11.

Micanovic, R., LaFavers, K., Garimella, P.S., Wu, X.R., El-Achkar, T.M., 2019. Uromodulin (Tamm-Horsfall protein): guardian of urinary and systemic homeostasis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Patidar, K.R., Garimella, P.S., Macedo, E., Slaven, J.E., Ghabril, M.S., Weber, R.E., Anderson, M., Orman, E.S., Nephew, L.D., Desai, A.P., Chalasani, N.P., El-Achkar, T.M., 2019. Admission plasma uromodulin and the risk of acute kidney injury in hospitalized patients with cirrhosis: a pilot study. American journal of physiology. Gastrointestinal and liver physiology 317, G447-g452.

Winfree, S., Dagher, P.C., Dunn, K.W., Eadon, M.T., Ferkowicz, M., Barwinska, D., Kelly, K.J., Sutton, T.A., El-Achkar, T.M., 2018. Quantitative Large-Scale Three-Dimensional Imaging of Human Kidney Biopsies: A Bridge to Precision Medicine in Kidney Disease. Nephron 140, 134-139.

Winfree S, et al. (2017) Large-scale 3-dimensional quantitative imaging of tissues: state-of-the-art and translational implications. Transl Res. 2017 Nov;189:1-12
Winfree S, et al (2017) Quantitative Three-Dimensional Tissue Cytometry to Study Kidney Tissue and Resident Immune Cells. J Am Soc Nephrol. 2017 Jul;28(7):2108-2118